Evaluation of biosurfactant potential from Brevibacillus sp AVN13 for remediation of hydrocarbons and heavy metals

Bioremediation with the help of biosurfactant is one of the promising technologies in treating the hydrocarbon and heavy metal contaminated sites.Biosurfactant was produced naturally by microorganism and hence biodegradable, which is alternative to chemical surfactant for various applications.In this study the biosurfactant producing strain Breviba

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Multiple virtual screening approaches for finding new Hepatitis c virus RNA-dependent RNA polymerase inhibitors: Structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors

Abstract The RNA polymerase NS5B of Hepatitis C virus (HCV) is a well-characterised drug target with an active site and four allosteric binding sites.This work presents a workflow for virtual screening and its application to Drug Bank screening targeting the Hepatitis C Virus (HCV) CS-1708 RNA polymerase non-nucleoside binding sites.Potential polyp

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